A potent, orally active, balanced affinity angiotensin II AT1 antagonist and AT2 binding inhibitor

J Med Chem. 1993 Oct 15;36(21):3207-10. doi: 10.1021/jm00073a024.
No abstract available

MeSH terms

  • Administration, Oral
  • Angiotensin II / antagonists & inhibitors*
  • Angiotensin Receptor Antagonists
  • Animals
  • Binding Sites
  • Quinazolines / chemical synthesis
  • Quinazolines / metabolism
  • Quinazolines / pharmacology*
  • Rabbits
  • Rats
  • Receptors, Angiotensin / metabolism
  • Renin-Angiotensin System / drug effects

Substances

  • Angiotensin Receptor Antagonists
  • Quinazolines
  • Receptors, Angiotensin
  • Angiotensin II